Amplatzer Occluder Therapy
Patients diagnosed with atrial septal defect (ASD) closure with an Amplatzer occluder exhibit both:
- Echocardiographic evidence of ostium secundum ASD
- Clinical evidence of right ventricular (RV) volume overload (ie, ratio of pulmonary over systemic flow > 1.5 or RV enlargement
ASD is one of the most common congenital heart defects that requires intervention—and intervention is critical, since the mortality rate from untreated, hemodynamically significant ASD can approach 25%.1
ASD is one of the most common congenital heart defects that requires intervention—and intervention is critical, since the mortality rate from untreated, hemodynamically significant ASD can approach 25%.1
Patient Experience after Atrial Septal Defect Occlusion
Patients typically report symptom improvement after the closure of the ASD. In young children growth rate can increase, and in children and young adults LV filling improves. When younger patients are treated—those who have less chamber enlargement before repair—there is greater likelihood of normalization of RV size.
Although improvement is less pronounced in patients over age 60, they nonetheless report symptomatic improvement.
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- Turner DR, et al. Closure of secundum atrial septal defects with the Amplatzer Septal Occluder: a prospective, multicenter, post-approval study. Circ Cardiovasc Interv. 2017;10:e004212.